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KMID : 1094020160330060392
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Journal of Veterinary Clinics
2016 Volume.33 No. 6 p.392 ~ p.394
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A Case of Cyclosporine Treatment in Cat with Allergic Dermatitis, Nonresponsive to Prednisolone Treatment
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Ryu Dong-Wook
Kang Joo-Yeon
Ko Min-Ho
Cho Hyun-Kee
Chung Jin-Young
Han Jeong-Hee
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Abstract
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A 2-year-old spayed female Persian cat presented to Kangwon National University Veterinary MedicalTeaching Hospital with pruritus and erythema on the tips of both ears, around the eyes, and in the caudal abdomen. This patient had previously been prescribed prednisolone, but did not respond positively to the treatment. A skinscreening test revealed that there were no fleas or fungi, and that only cocci were present. Blood testing revealedno remarkable findings. The patient was prescribed antibiotics (amoxicillin-clavulanic acid 25 mg/kg for 2 weeks) withno prednisolone. After 2 weeks, clinical signs were alleviated and the skin screening test showed no signs of cocci. However, clinical signs recurred even with the prescription of antibiotics. Four weeks after the steroid-free interval,Malassezia spp. hypersensitivity was detected upon a serum allergy test, and pathological analysis confirmed eosinophilicand mastocytic superficial dermatitis in the caudal abdomen. Based on these results, we suspected allergic dermatitisand prescribed 7 mg/kg cyclosporine A once a day. After 3 weeks, clinical signs were resolved. Seven weeks afterthe first trial with cyclosporine A, we reduced the cyclosporine A dose to 7 mg/kg every other day. The patient’ssymptoms have since been well controlled for 6 months. This study suggests that cyclosporine A can be a good choicefor treating cats with suspected allergic dermatitis that has not responded positively to steroid treatment.
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KEYWORD
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Allergic Dermatitis, Cat, Cyclosporine A.
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